RESUMO
Pathologic background has been evaluated for premature delivery of 38-39, 30-37 and 20-27 week fetuses. The trial involved 115 placentas in abortion and 60 control cases of normal pregnancy. A combination of modern techniques involving histological, enzymatic and chemical has been employed as well as light microscopy. The destructive, compensatory and adjustment processes observed in the placentas were correlated topographically. The parameters registered were compared to clinical and laboratory findings. The structural basis has been defined for compensatory alterations in the placenta and pathomorphological criteria have been derived for progressive functional insufficiency at various gestation periods.
Assuntos
Aborto Espontâneo/patologia , Placenta/patologia , Ameaça de Aborto/patologia , Feminino , Humanos , Microscopia Eletrônica , Trabalho de Parto Prematuro/patologia , Gravidez , Segundo Trimestre da Gravidez , Terceiro Trimestre da GravidezRESUMO
Scanning electron microscopy was used to study the microrelief of the intima of coronary arteries in 11 cases of sudden death due to acute coronary insufficiency. In areas of macroscopically intact intima and in zones of minimal atherosclerotic lesions in patients dying of acute coronary insufficiency there were disorganization of intima microrelief with zones of flattening of folds of the first order, the appearance of microplaques with ulceration, dystrophic calcification which reflect early manifestations of coronary artery atherosclerosis. Another group of lesions (diendothelization of the intima with initial signs of parietal thrombus formation) characterizes the functional state of the vessel and serves an indirect criterion of acutely developing spasm of the coronary artery.
